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Themed collection Coronavirus articles - free to access collection

156 items - Showing page 1 of 3
Editorial

Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research

《危险!》(Jeopardy!):这个游戏节目今年已播出50年(1964年3月30日首播),它证明自己不仅能难住观众,而且能令他们感到意外。不仅是因为主持人亚历克斯·特里贝克(Alex Trebek)留起了胡子(之前13年他都是把胡子剃得干干净净),而且是因为仍有些选手表明自己能刺激观众。今年刺激观众的是亚瑟·朱(Arthur Chu),他采用闪电战式的答题方式,在网上引起一片哗然。他的策略令人兴奋,当然也很奏效:他在锦标赛中夺得第二名(友善的本·因格拉姆[Ben Ingram]最后得了第一)。
Apple CEO Tim Cook

Graphical abstract: Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Editorial

Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?

你的老板有望学会使用Twitter
A study published in the journal "Clinical Psychological Science" in 2012 showcased the power of self-imagination, which showed the technique could help people with impaired memories, as well as individuals with no memory problems. As with other studies of human memory, the scientists asked participants to remember a list of words related to certain personality traits. The participants were then asked to use a specific strategy to help them recall the words. For example, some participants were asked to remember one personality trait by thinking of a second word that rhymed with the trait. Other participants were asked to remember the definition of the trait while others were asked to engage in "self-referential processing" where they would think about the trait in a personal, self-reflective way.

Graphical abstract: Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Open Access Accepted Manuscript - Highlight

Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities

Open Access Perspective

Soft matter science and the COVID-19 pandemic

总排名76位的新加坡管理大学(Singapore Management University)李光前商学院(Lee Kong Chian School of Business)是首家进入这一排行榜的新加坡商学院。今年共7家亚洲商学院上榜。李光前商学院校友在亚洲商学院中最具国际流动性。他们在流动性指标方面排名第25,比在亚洲商学院中流动性排第二的台湾国立中山大学(National Sun Yat-Sen University)高57位。

Graphical abstract: Soft matter science and the COVID-19 pandemic
Open Access Perspective

Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective

No students or teachers drank the poisoned water, the report said.

Graphical abstract: Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
From the themed collection: 热地不断 新市府楼市加速上行
Perspective

Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic

The three bubbles: The Asian Bubble in the early '90s, Dot-com Bubble of the late '90s and what Juckes calls the Great Big Credit Bubble that triggered the 2008 Wall Street meltdown.
3) I am often irritated 0 1 2 3 4
然而,他认为,“在解释新兴市场危机的发生率时,美国的货币政策往往与新兴市场国内因素同样重要——如果不是更重要的话。”
Tracey and Viv Williams, a British couple, dressed as the green cartoon ogres from Shrek at their wedding held recently. Tracy, 33, made a lovely Princess Fion

Graphical abstract: Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Perspective

Trends and targets in antiviral phototherapy

3.别理会那些出现在CNN国际频道里、告诉你英国行为规范的打领结的专家。这些家伙通常来历不明,自己住在美国加州,却试图提供一些要么不相干要么过时了的建议。比如说,他们通常会告诉你,英国人喜欢排队;喜欢说对不起,即使有时候并不是他们的错误。而事实上,英国人也喜欢插队,而且还会用咳嗽把排在他们后面的人也吓跑。这取决于天气有多闷热潮湿。
伦敦商学院今年在英国《金融时报》每年发布的4项排名中的表现,令其在欧洲最优秀的81所商学院中拔得头筹,这4项排名是:MBA、高管MBA(EMBA)、管理硕士(MiM)以及高管教育。(有两所商学院因得分相同并列第80位。)
《人物》评选的电影史上35位美人(1)
但当格雷泽给我们带来《皮囊之下》,这部经过他长期酝酿的,由荷兰作家米歇尔·法柏的科幻小说改编的电影时,真是让人惊叹:欢快,不安,大胆。斯嘉丽扮演的外星人藏于人类的皮囊里,穿梭在格拉斯哥街道和商场,不亚于一位一线明星。现实生活中的路人在镜头中完美的展现,而隐身的约翰森面无表情的估算着三个地球人可被利用的热量值。接着演员带着被色诱的人类离开人群,来到她自己的地方:一个神秘的黑暗的洞穴中。在这里,情色恍惚间,人类贡献自己的肉体,被囚禁,被养殖成为食物,谁知道呢,又或许是人类的灵魂。

Graphical abstract: Trends and targets in antiviral phototherapy
Minireview

A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays

曼谷在2014-15年排行下降主要是由于近年来的政治不稳定。

Graphical abstract: A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Minireview

Novel biosensing methodologies for ultrasensitive detection of viruses

"The only thing she's got is the woman card," Trump said. "I'd love to see a woman president, but she's the wrong person. She's a disaster."

Graphical abstract: Novel biosensing methodologies for ultrasensitive detection of viruses
Application

Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug

蕾哈娜在榜单上排名第二,获得亚军,《男人装》表示:在这12个月以来,她真是无处不在,但是我们依然没有对她审美疲劳。
The pair stand on opposite sides backstage and memorize the winners to avoid having to write them down and have revealed in the past how they carry out rigorous checks to ensure they have stuffed the envelopes correctly. It is believed Ruiz and Cullinan are ordered to destroy the duplicate cards as the presentation goes on, so by the time Best Picture is awarded, the only envelopes left are the two for Best Picture.

Graphical abstract: Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
Open Access Review Article

ACE2 as a potential therapeutic target for pandemic COVID-19

Zhaopin.com received 93,420 effective samples for the survey, which covered new grads completing higher vocational, undergraduate, master's or doctoral programs.
Talking to Town & Country, Industry Kitchen Executive Chef Braulio Bunay said he was inspired to create the pizza by the city's Financial District, which he described as 'the epitome of decadence'.

Graphical abstract: ACE2 as a potential therapeutic target for pandemic COVID-19
Open Access Review Article

Diagnostic technologies for COVID-19: a review

移动端取代网页端。
In an emailed statement, FIFA said that during group stage matches, it sold a total of 143,364 of the cheapest tickets, which amounted to roughly 3,000 such tickets available per match.

Graphical abstract: Diagnostic technologies for COVID-19: a review
Open Access Review Article

Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review

The aspiring actress is also hoping her online following will secure her an audition to appear on ABC show 'Once Upon A time' which is adding Elsa as a character next season.
史赛克公司(Stryker)的创始人就是“翻身床”的发明者,借助这个设备,卧床的病人无需挪动身体就能改变在病床上的位置。顺其自然地,这家医疗设备制造商也向自家员工及其家属出借医疗床,分毫不收。
它促使特朗普当选不仅与选举中的投票数不符,而且也没有反映出亚历山大.汉密尔顿(Alexander Hamilton)想要的那种对候选人德行的判断。
动作、探险剧《盗墓笔记》改编自徐磊(笔名南派三叔)的畅销网络小说。它也是中国第一部季播网络剧,预计该小说将被改编为8季,每年播出一季。第一季于2015年6月播出。同名系列小说讲诉了吴邪和小伙伴们在古墓探险的故事,该小说2006年在网上发布后受到了大量粉丝的追捧。因此,大家对改编电视剧期望颇高,不过它却让粉丝们大跌眼镜。尽管首播2分钟后,网络点击量就超过了2千4百万,不过第一季的薄弱情节和粗劣品质很快就被粉丝们炮轰了。剧中的一些台词甚至成了社交媒体上调侃的段子。

Graphical abstract: Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
Open Access Review Article

An overview of key potential therapeutic strategies for combat in the COVID-19 battle

愿新年的烛光带给你祥和与喜悦,祝你新年充满爱。

Graphical abstract: An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Open Access Review Article

Potential repurposed SARS-CoV-2 (COVID-19) infection drugs

(美联社)波多黎各,圣胡安市 - 波多黎各新总督周一宣誓就职,作为美国领土许多人认为要为新的紧缩措施做准备,并为该岛摆脱严重的经济危机重新推动建州或独立。
金州勇士队的控球后卫史蒂芬·库里表示,自2013年开始,他每年都会前往中国,而中国的篮球迷也都非常支持他。

Graphical abstract: Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
From the themed collection: 房企“地产+”转型难寻坦途
Open Access Review Article

Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale

Asli Erdogan, a novelist of the “dark, pessimistic,” is struggling to process her own grim experience: months in prison.

Graphical abstract: Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
Review Article

In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections

"Some geniuses in the internet industry created miracles, but that does not tell the whole story," said Chen. "Business has its own rules. Before you start up, you have to know how to produce products, how to sell them, how to manage a company. Those lessons you cannot expect a fresh graduate to know."

Graphical abstract: In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Review Article

Antiviral drug discovery: broad-spectrum drugs from nature

Microscopic as the subjects are, the benefits of the scientists’ research are set to be huge.
1."The Little Kicks" in Seinfeld Almost Didn't Happen
4.Candice Swanepoel
They say that it is especially risky to use the same password for entertainment sites as for email and social networking accounts.

Graphical abstract: Antiviral drug discovery: broad-spectrum drugs from nature
From the themed collection: 2015年全球照明行业的6大新突破
Review Article

Influenza neuraminidase: A druggable target for natural products

28 September
Dua Lipa, 'Dua Lipa'
Maddie has now appeared in three of Sia's videos - Chandelier, Elastic Heart and Big Girls Cry.
We learned about the causes and consequences of rising obesity around the world.
我们必须牢牢抓住就业这一民生之本,让人们在劳动中创造财富,在奋斗中实现人生价值。

Graphical abstract: Influenza neuraminidase: A druggable target for natural products
Critical Review

Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle

5. Will China's migrant workers get permanent urban residence in 2010?
如果你很卖命的工作并且给公司创造了价值,你本应该得到酬谢。如果你的老板在两年之内没有给你涨薪水,去申请吧。如果老板不同意,还考虑什么,走吧。

Graphical abstract: Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
From the themed collection: 杭州进一步加强房地产中介监管
Critical Review

The role of biosensors in the detection of emerging infectious diseases

然而一般情况下,你只需注意洗衣机是否停止发出噪声就能来判断洗衣服是否结束。另外你也只要抬头一看外面的天气或者看一下天气预报app,就能知道是否会下雨了。因此,这个产品基本上只是一种黑客进入你家的方式。

Graphical abstract: The role of biosensors in the detection of emerging infectious diseases
Communication

Quantitative determination of mechanical stability in the novel coronavirus spike protein

According to the announcement, the new administrative center in Tongzhou will put infrastructure upgrades and ecological improvement on top of the agenda. The municipal government hopes to improve public services in education, healthcare, cultural events and industries in the district.

Graphical abstract: Quantitative determination of mechanical stability in the novel coronavirus spike protein
Communication

Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations

(传说中的中心对称!!!!)不过Illuminati的对称文已经遗失,下面的对称文是Dan Brown在写《天使与魔鬼》的时候找朋友设计的。 就《天使与魔鬼》一书描述,尽管很多人怀疑该组织的真实性,但光照派的确存在,至今如此,并且已经渗入了当今各个领域,尤其是很多共济会成员都在其中。
Despite the fact that each market rebound ended up as a V-shaped affair, each successive rally was carried out with less and less individual stock participation. Glaring divergences between winners and losers, large caps and small caps, preoccupied the commentariat for most of the spring and summer. Deflationary concerns from Europe and the Japanese technical recession further confounded analysts, as Treasury yields and inflation indicators in the U.S. were driven lower despite the improving domestic economy.
这一新数据公布之际,杜特尔特正抵御国内外对其禁毒运动的指责,已有60万名潜在嫌疑人向当局自首。
talented

Graphical abstract: Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
Communication

MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling

该工作室称,他们已经采取了措施,因为这个男孩拒绝删除发布在youtube上的视频,而在这个视频中他向人们介绍了如何去使用这个软件。
It's quite an odd question, because Ireally wanted to start writing when I read lots of Stephen King stories. Hisstories were quite astonishing and interesting.
On Turkey, which recently shot down a Russian warplane, Putin said he sees no possibility of overcoming the strained ties with the current Turkish leadership. He said he was shocked to see that Turkey hadn't tried to explain its action but turned to help from NATO instead.
Soon after the conclusion of the 2016 national post-graduate entrance examination on Sunday, the Ministry of Education was informed of suspected leaks of exam questions.

Graphical abstract: MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Communication

Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses

"It sounds like Harvard is intruding too deeply into the private lives of students," said Dershowitz, who has represented a series of high-profile clients, including OJ Simpson.
玛莎·切利取出嘴里的香烟,喃喃低语:"我也曾经这么想过。"说完便又抽起了烟。马克震惊了(我们想象一下,当知道你的亲生母亲可能会在你沐浴时杀了你,这反应很正常)。马克第一次意识到家庭主妇会变得多么绝望和孤独。接着,他就想到这会是电视剧的一个好素材。这次谈话便开启了《绝望主妇》的制作。

Graphical abstract: Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Communication

Inhibition of SARS coronavirus helicase by bismuth complexes

7月25日
Most Catholics (60 percent) and white non-evangelical Protestants (65 percent) say they believe disasters like hurricanes and floods are the result of climate change.
Hurricane Harvey
Usually sober-minded analysts, accustomed to the auto industry’s slow growth, seem to shed their inhibitions when it comes to Tesla. Rod Lache of Deutsche Bank has attached a $310 price target on the stock. Not to be out-done, Adam Jonas of Morgan Stanley established a $320 price target and calls Tesla it the “most important car company in the world”.
寻找工作的雇员并不希望将这些蛛丝马迹被他们的经理发现,凯说,但是他们确实被发现了。

Graphical abstract: Inhibition of SARS coronavirus helicase by bismuth complexes
From the themed collection: 中国建材行业一周大事记(9.14-9.20)
Open Access Edge Article

Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning

Besides, Japan and the United States are still innovation hot spots and chemical, semiconductor and electronic components and autos are the top innovative industries, according to the report.
“食品批发价格显示,上月,猪肉、蔬菜和水果的价格上涨都有所放缓,”凯投宏观(Capital Economics)在CPI数据公布前表示。
但是受访者也指出,社交媒体使得他们读的书更少了、视力受到影响、睡眠更少、隐私遭到泄露以及其他一些问题。

Graphical abstract: Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
Open Access Edge Article

A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers

We will make a big push for progress in the reform of the social system.
Plante Moran

Graphical abstract: A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
From the themed collection: 楼市库存跌至近年最低
Open Access Edge Article

Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods

The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.

Graphical abstract: Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
From the themed collection: 楼市“初春”谨防热炒
Open Access Edge Article

Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors

By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.

Graphical abstract: Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
Open Access Edge Article

Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir

identified
[ru:t]
眼下,合格的供应链经理极度缺乏,在那些分支机构遍布全球的跨国公司中尤其如此。究其原因,不外以下两点。

Graphical abstract: Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
Open Access Edge Article

Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes

Seven schools made it back into the top 100 after having missed out in the past year or two.
与此同时,苹果正在引入昂贵的新组件,包括OLED显示屏,使手机正面成为一个连续屏幕。深度感应摄像头将提供“增强现实”新功能,并允许手机通过人脸识别(而不是指纹)解锁。
Will the Democrats take back the majority in the midterm election in the US House of Representatives

Graphical abstract: Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
Accepted Manuscript - Paper

A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring

From the themed collection: 国务院:稳慎改革农村宅基地制度
Open Access Paper

Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)

津巴布韦新任领导人会举行公平的选举并胜选吗?

Graphical abstract: Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
Paper

A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood

About 40 per cent of entrepreneurs did not seek any help when securing finance. Half of these raised equity purely from their own savings and/or family and friends compared with only 40 per cent of those who sought help from the school or alumni network.

Graphical abstract: A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Open Access Paper

Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations

Lots of managers recalled extreme etiquette errors. The applicant
在美国,纽约州、加利福尼亚州和得克萨斯州获得最多投资。中国企业在头号投资目的地纽约投资54亿美元,其中大部分投入三笔大规模金融服务和房地产交易。

Graphical abstract: Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
Open Access Paper

The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives

No. This is possible, of course, but with luck, Mrs May has at least now ensured that the UK is not going to tumble over a “no deal” cliff in 2019. In December 2017, Consensus Forecasts’ prediction for the UK was of 1.5 per cent growth in 2018. Its forecasts for Japan and Italy were even lower, at 1.3 per cent. So the chances that the UK will have the slowest-growing economy in the G7 next year should be around one in four.
2008年,中国政府增加了一个归类为精神疾病的条目:"网瘾症"。据大量官方媒体报道,中国的年轻人花太多时间泡在网吧里,不顾家人和工作玩网络游戏到凌晨,有时甚至不吃,不喝,不睡眠,严重危害了自己的健康。
周四,央视公布了2016猴年春晚的吉祥物后,就迅速成为互联网上的热议话题。不幸的是,不少网友称被其“丑哭”。
愿新年带给你和你所爱的人许多美好的事物和无尽的祝福!

Graphical abstract: The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
Open Access Paper

Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease

出口的提振在很大程度上源自对美出口,其价值自3月份以来首次出现同比增长,同比增6.9%,至368亿美元。在其他出口目的地中,对欧盟出口同比增长5.1%,至299亿美元,对日本出口同比增长3.2%,至122亿美元。
Despots use the former as an excuse for repression and the latter to demand absolute obedience.

Graphical abstract: Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
Open Access Paper

Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro

在春运期间,国内的交通运输将面临极大的挑战,车票供小于求。铁路局会采取多种措施来应对春运压力,比如开设临客(L字头的列车)、延长售票时间以及开设更多的售票点。
reservation

Graphical abstract: Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
Open Access Paper

Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein

中国力争达成自己的亚太区协议

Graphical abstract: Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Paper

Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide

This year the list features nine heads of state who run nations with a combined GDP of $11.8 trillion — including the No. 1 Power Woman, German Chancellor Angela Merkel. The 24 corporate CEOs control $893 billion in annual revenues, and 16 of the women here founded their own companies, including two of the three new billionaires to the list, Tory Burch and Spanx’s Sara Blakely. Speaking of, this year’s class has 14 billionaires valued in excess of $82 billion.
成功的创业者需要付出努力和毅力,因为非常不幸的是,世上并没有创业小精灵,能够神奇般地将成功赐予小公司和他们的老板。
在上月销量最高的SUV和MPV制造商中,大家所熟悉的长城汽车和上汽通用五菱汽车成功卫冕。在轿车和掀背车型上,上汽大众也保持其冠军地位。
The Olympic games are a time when the countries of the world should put aside their differences to engage in sport. Whether that actually happens, however, is debatable. While the athletes are surely capable of focusing on the competition, it can be hard for long-standing disagreements to be forgotten -- even temporarily -- by their home countries.

Graphical abstract: Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
Open Access Paper

Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses

目前已经得到证实的是,胡歌将会加盟该电影,继续出演主角“李逍遥”,而女主角的扮演者暂时还未透露。
Anxiety about addiction to screen time gave rise to a dubious new line of businesses: boot camps, often run by ex-military personnel, promising to help wayward youth kick the habit. But investigative reports p ublished in recent days by Beijing News and the Mirror reveal abusive conditions, leading to the death of at least one student, at the Zhengzhou Boqiang New Idea Life Training School, which billed itself a s an Internet-addiction recovery camp in eastern Henan province.

Graphical abstract: Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
Open Access Paper

The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor

Falke的最终失利令人扼腕,但eBay的表现确实无可匹敌。我以为自己对eBay的爱将矢志不渝,因为鄙人全部的穿戴和家中物件均来自这家公司,而它却向《纽约时报》(the New York Times)表示:“我们热切希望利用我们的平台,通过营造公平的竞争环境来造福数百万人。”
凯莎《彩虹》
如果你很卖命的工作并且给公司创造了价值,你本应该得到酬谢。如果你的老板在两年之内没有给你涨薪水,去申请吧。如果老板不同意,还考虑什么,走吧。

Graphical abstract: The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
Open Access Paper

Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study

In addition to WeChat's core private and group messaging functions, users can also find new contacts by using the application's Drift Bottle function, where a user records a message and sends it out to see in a virtual bottle for a stranger to pick up and respond. Its Look Around function, similar to some mobile dating applications, allows users to browse the profiles of other users who are in close proximity. It also has a function called Moments that allows users to share photo albums publicly with groups of contacts, much like photo-sharing application Instagram.
在1981年,全球52%的人极其穷困潦倒。这个数字在2010年的时候下降了21%,少于7.21亿人还过着极度贫困的生活。
在接受《每日电讯报》采访时,玛蒂说:“我再也无法过上平凡人的生活了。因为大家很容易认出我来,甚至当我出去玩或是和朋友吃冰淇淋都能被路人认出来。”

Graphical abstract: Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Open Access Paper

Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework

正是由于零部件的不断缩小,这些科技设备的运算效率才得以释放,让它火遍全球。
Singer Susan Boyle came undone -- literally, when her trousers popped open at a soccer match as she waved a Celtic fan above her head in Scotland. The "Britain

Graphical abstract: Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Open Access Paper

Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach

Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.

Graphical abstract: Several coumarin derivatives and their Pd(ii) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Open Access Paper

Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors

Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.

Graphical abstract: Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Open Access Paper

Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins

Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.

Graphical abstract: Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Open Access Paper

Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform

TV soaps regularly top the TV ratings but the highest trending show of 2012 was the BBC kids' show 'Mike The Knight' that beat US terror drama 'Homeland' and 'Towie.'
Analysts say headline import figures may start to improve in the coming months since commodity price falls were particularly pronounced at the end of 2014, which will mean smaller year-on-year falls in Chinese imports in value terms.
凯特 阿普顿

Graphical abstract: Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
Open Access Paper

A modular microarray imaging system for highly specific COVID-19 antibody testing

Recent initiatives to support two-way tourism between the two countries include the trial of the 10-year visitor visa; the open aviation market services arrangement which removes all capacity restrictions for airlines on both sides; and a new Beijing to Sydney service by Qantas Airways which was launched in January.
Staff numbers at insurance agencies also rose by 936,200 to a total of more than 5.6m people.

Graphical abstract: A modular microarray imaging system for highly specific COVID-19 antibody testing
Open Access Paper

Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms

Will China's stock market climb back to the 6,000-point mark it reached two years ago? The stock market was at its most bullish back then, but if you ask the same question now, some would cite a global economy still reeling from a recession.
The spread of HIV through drug injections has been effectively controlled. In 2017, the number of people infected through drug abuse was 44.5 percent lower than that in 2012.
Let’s now travel to Greece. There, Andreas Georgiou, the head of its statistical agency between 2010 and 2015, faces prosecutions for his part in uncovering fake Greek public finance data for 2009 and setting the record straight. This week 40 groups, led by the American Statistical Association, and 651 individuals signed a statement in support of Mr Georgiou.

Graphical abstract: Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
Open Access Paper

Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening

But back to TextPride. Wray and O’Brien saw the way users eagerly engaged with their branded emojis, and believed advertisers appreciated the convenience of using one vendor to get many different messaging apps. But they realized that that was only half of the business. For certain established brands like sports teams, people will pay for stickers. But other, unknown brands would pay just to be included.

Graphical abstract: Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Open Access Paper

Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations

A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.

Graphical abstract: Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
Open Access Paper

Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets

沃伦·巴菲特自2014年以来再次排名第二,净资产由去年的608亿美元增加到756亿美元。
However, another 876 jobs being offered have not registered a single applicant as of Tuesday, according to Zhonggong. For instance, nobody has so far shown any interest in becoming a railway police officer in Shanghai and Xi'an.

Graphical abstract: Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
Open Access Paper

A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation

[iks'p?nn]
Online registration for the 2017 national civil servant exam started last Saturday.

Graphical abstract: A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
Open Access Paper

An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19

3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.

Graphical abstract: An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
From the themed collection: 北京个人租房贷款最高100万元
Open Access Paper

Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies

While organizers of the show attempt to get it back on track following a string of problems obtaining visas for models and performers such as Gigi Hadid and Katy Perry, now they're also claiming that their e-mails are being intercepted by Chinese authorities.
说到这一点,你要注意的是,不要影响其他的人。没有人想每隔十分钟就听到你提问一次。如果你实在是不懂的话,可以在课后约上老师再讨论。

Graphical abstract: Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Paper

Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material

艾伦是一名优秀的喜剧演员并凭借自2003年起主持由她自己名字命名的脱口秀节目而被观众喜爱熟知。
今年最令人惊喜的消息还包括油价下跌。经济学家对油价下跌的经济影响也是见仁见智,一方面认为消费者因此节省了不少油钱,一方面则认为这种趋势会影响石油的开采钻探活动。但大家普遍认为这会影响小型车和混合动力车的销量。油价下跌加上车价过高,使得凯迪拉克公司的电动轿跑ELR稳居2014年最不受欢迎的车型“宝座”。11月份,这款售价高达8万美元的电动跑车只卖出了155辆。

Graphical abstract: Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
From the themed collection: 进口家具市场混乱 阻碍消费购买
Open Access Paper

A facile assay for rapid detection of COVID-19 antibodies

Yet, the disparity in haircuts lasted for almost two years. In fact, the pessimism and risk-aversion of the Seppenwolde lenders reduced the overall availability of leverage in Amsterdam.

Graphical abstract: A facile assay for rapid detection of COVID-19 antibodies
Open Access Paper

Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses

World's Most International Universities Ranking 2016 by The Times Higher Education included 200 universities from 28 countries. It employed indicators such as the proportion of international staff, the number of international students and research papers published with at least one co-author from another country of each institution.
Subdivided flats smaller than 100 square feet (9 square meters) can rent for $385 in the Asian city.
国家新闻出版广电总局官员表示,中国电影业在2016年经济发展“新常态”下保持了稳定的发展势头。
A combination of tax increases and spending cuts in 2013 shaved about 1.5 percentage points off annual economic growth, according to the Congressional Budget Office. Many forecasters expect the fiscal drag in 2014 to be one-third that amount, or less. 'You'll have more political certainty this year,' said Gregory Daco, a U.S. economist at Oxford Economics.

Graphical abstract: Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
Open Access Paper

Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2

在全球,中国将会进一步进行并购和交易。在非洲,1百万中国人在努力获取自然资源。

Graphical abstract: Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
From the themed collection: 七类投机炒房行为将被严打
Open Access Paper

Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease

HSBC economist Hongbin Qu said the survey pointed to lost momentum in China's manufacturing sector: He expects Beijing to respond with measures to counteract the slowdown.
卡尔说:“如果要打赌的话,我赌今年比去年更热。”
Last week, Clinton campaign chairman John Podesta said that the former first lady's shortlist of potential running mates will include women, quickly leading to speculation that Clinton will consider Massachusetts Sen. Elizabeth Warren, a popular progressive, for an all-female ticket.

Graphical abstract: Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
Open Access Paper

Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19

据信,宝能借入了大笔资金来购买万科的股票。现在,它已是万科最大的股东,持股比例为25%。
Employment is crucial to ensuring people’s well-being. We will focus our efforts on facilitating employment to see that through their hard work, people can create wealth and realize their full potential.

Graphical abstract: Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Paper

Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties

n. 浪漫的人
比蒂在后台说:“这真是我遇到的最离奇的一糟事。感谢上帝!幸好是我们两个人在那里!”

Graphical abstract: Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Open Access Paper

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.

Graphical abstract: Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
From the themed collection: 碧桂园下乡
Paper

Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract

['v?:tju:]

Graphical abstract: Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Open Access Paper

Anti-HIV drug repurposing against SARS-CoV-2

China in 2012: fixated on stability as the pressures mount without and within.
CONTACT: Kathy Michalove, Seaboard Properties, (860) 535-8364; seaboardpropertiesre.com
在本届达沃斯世界经济论坛(World Economic Forum)盛大闭幕会议上,与会者承认风险的存在,认为缺乏有效管理的新兴市场很容易受到危机冲击,但他们最终得出的结论是,前景是多年来最为光明的。

Graphical abstract: Anti-HIV drug repurposing against SARS-CoV-2
Paper

Length-scale dependence of protein hydration-shell density

The Bellarine Peninsula, located Southwest of Melbourne, Victoria, has been a hotspot for timeless beaches and historic towns like Queenscliff and Portarlington.
有趣的是,一项调查发现,31.8%的受访者认为北京是中国最拥堵的城市,而8.8%的人则认为郑州是中国最拥堵的城市。
The values of the citizenry are a democracy’s most important asset.
美国时间上周日,乡村音乐界的大牌们齐聚拉斯维加斯,出席2013年乡村音乐学院奖颁奖典礼。

Graphical abstract: Length-scale dependence of protein hydration-shell density
Open Access Paper

High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus

研究人员表示,去年之所以特别引人瞩目,是因为除了1月和4月以外,每个月都会创下新的全球高温记录,或与记录持平。
此外,他指出,鉴于中国正在努力推动本国经济从出口转向消费的再平衡(从而减少对中间投入品的进口需求),再加上“中国政府鼓励使用国内供应商的政策”和其他地区保护主义的兴起,“全球贸易在短期内不太可能回暖”。

Graphical abstract: High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
Paper

A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor

有专门的机器将氦气打入制作泡沫的溶液中。
Among these six US schools, Rutgers Business School in New Jersey is the highest new entrant at 70. WP Carey School of Business at Arizona State University is the highest returning school at 57. Moore School of Business at the University of South Carolina returns at 77. Moore stands out for being top overall for international course experience. Its students spend from several months to a year overseas.
10月份中国非制造业商务活动指数(非制造业PMI)为54.3,低于9月份55.4的近期峰值。其中,服务业商务活动指数为53.5,比9月份的峰值回落0.9个百分点。就连建筑业的形势似乎也有所恶化,商务活动指数为58.5,较9月份回落2.6个百分点。

Graphical abstract: A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
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n. [计]定序;排序;订购 v. 命令;指挥;订购(o
9) Well Done: It’s a cliché, no doubt. Sometimes, it isn’t enough just to say thanks. People want to know what they did was great and why. They pour so much sweat and soul into their projects.They need to know their work was special and had meaning to someone.

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